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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP20A1 All Species: 8.48
Human Site: Y127 Identified Species: 15.56
UniProt: Q6UW02 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UW02 NP_803882.1 462 52432 Y127 N H M R K K L Y E N G V T D S
Chimpanzee Pan troglodytes Q8HYN1 508 57365 Q148 K L E K I I C Q E I S T L C D
Rhesus Macaque Macaca mulatta XP_001105388 458 51229 A127 K E E G D G A A G A G R R G P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BKE6 462 52131 Y127 D H V R R K L Y G D A V T A S
Rat Rattus norvegicus Q6P7D4 462 51979 Y127 D H V R R R L Y G D A V T A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506190 262 29719
Chicken Gallus gallus XP_426572 463 52409 L127 E S H L R R K L Y E S G V S K
Frog Xenopus laevis NP_001079548 463 52021 L127 E S H V Q K K L Y E N G I T K
Zebra Danio Brachydanio rerio NP_998497 462 51647 V127 E S M M R K K V Y E G A I N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VXY0 495 57171 T128 H R R R K L L T P G F H F R I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792896 231 25756
Poplar Tree Populus trichocarpa XP_002300926 460 52070 A125 F H F I N T V A M E T L D Q W
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65790 500 57537 F141 S S H R L I N F Q H I R K D E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.2 60.6 N.A. N.A. 83.1 81.8 N.A. 42.6 73.6 73.2 63.8 N.A. 21 N.A. N.A. 23.1
Protein Similarity: 100 42.7 65.8 N.A. N.A. 90.6 91.1 N.A. 50.6 88.7 88.3 81.5 N.A. 38.7 N.A. N.A. 36.3
P-Site Identity: 100 6.6 6.6 N.A. N.A. 53.3 40 N.A. 0 0 6.6 20 N.A. 20 N.A. N.A. 0
P-Site Similarity: 100 13.3 6.6 N.A. N.A. 80 80 N.A. 0 13.3 13.3 33.3 N.A. 26.6 N.A. N.A. 0
Percent
Protein Identity: 23.8 N.A. N.A. 22.4 N.A. N.A.
Protein Similarity: 42.8 N.A. N.A. 42.6 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 16 0 8 16 8 0 16 8 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % C
% Asp: 16 0 0 0 8 0 0 0 0 16 0 0 8 16 8 % D
% Glu: 24 8 16 0 0 0 0 0 16 31 0 0 0 0 8 % E
% Phe: 8 0 8 0 0 0 0 8 0 0 8 0 8 0 0 % F
% Gly: 0 0 0 8 0 8 0 0 24 8 24 16 0 8 0 % G
% His: 8 31 24 0 0 0 0 0 0 8 0 8 0 0 0 % H
% Ile: 0 0 0 8 8 16 0 0 0 8 8 0 16 0 8 % I
% Lys: 16 0 0 8 16 31 24 0 0 0 0 0 8 0 24 % K
% Leu: 0 8 0 8 8 8 31 16 0 0 0 8 8 0 0 % L
% Met: 0 0 16 8 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 8 0 8 0 0 8 8 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % P
% Gln: 0 0 0 0 8 0 0 8 8 0 0 0 0 8 0 % Q
% Arg: 0 8 8 39 31 16 0 0 0 0 0 16 8 8 0 % R
% Ser: 8 31 0 0 0 0 0 0 0 0 16 0 0 8 16 % S
% Thr: 0 0 0 0 0 8 0 8 0 0 8 8 24 8 0 % T
% Val: 0 0 16 8 0 0 8 8 0 0 0 24 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 0 24 24 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _